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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PFAS All Species: 30.61
Human Site: T816 Identified Species: 56.11
UniProt: O15067 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15067 NP_036525 1338 144724 T816 A A R V G T E T V R A P G S L
Chimpanzee Pan troglodytes XP_511854 1397 150781 T875 A A R V G T E T V R A P G S L
Rhesus Macaque Macaca mulatta XP_001112405 1335 144369 T816 A A R V G T E T V R A P G S L
Dog Lupus familis XP_850167 1368 147436 T816 A A R V G S E T V R A P G S L
Cat Felis silvestris
Mouse Mus musculus Q5SUR0 1337 144611 T815 A A R V G T E T V Q A P G S L
Rat Rattus norvegicus NP_001099261 1271 136879 T744 A A R V G T E T V P A P G S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038667 1314 142462 T805 A A R V S G E T V K A P G S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P35421 1354 148067 T824 A A K V G G E T I K S P G T L
Honey Bee Apis mellifera XP_625036 1243 138433 I749 A A R I G K D I V K A P G T L
Nematode Worm Caenorhab. elegans Q19311 1343 148611 V810 A V T A H G E V V K S P G T L
Sea Urchin Strong. purpuratus XP_781955 1205 129101 L707 T A T V T P D L K R P N G K G
Poplar Tree Populus trichocarpa XP_002315209 1377 150616 V865 A A H A G G E V V K A P G N L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M8D3 1387 151761 V876 A A H A D G E V V K A P G N L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.9 97.1 87.5 N.A. 88.5 84 N.A. N.A. N.A. N.A. 63.2 N.A. 50.5 50.1 47.5 52.4
Protein Similarity: 100 95.2 98 91.6 N.A. 92.8 88.6 N.A. N.A. N.A. N.A. 75.1 N.A. 66 66.2 64.1 65.4
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. 80 N.A. 60 60 40 26.6
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. N.A. N.A. 86.6 N.A. 93.3 86.6 60 33.3
Percent
Protein Identity: 50.3 N.A. N.A. 50.4 N.A. N.A.
Protein Similarity: 65.2 N.A. N.A. 65.3 N.A. N.A.
P-Site Identity: 60 N.A. N.A. 53.3 N.A. N.A.
P-Site Similarity: 73.3 N.A. N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 93 93 0 24 0 0 0 0 0 0 77 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 16 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 85 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 70 39 0 0 0 0 0 0 100 0 8 % G
% His: 0 0 16 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 8 8 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 8 0 0 8 47 0 0 0 8 0 % K
% Leu: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 93 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 16 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 8 8 93 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 62 0 0 0 0 0 0 39 0 0 0 0 0 % R
% Ser: 0 0 0 0 8 8 0 0 0 0 16 0 0 54 0 % S
% Thr: 8 0 16 0 8 39 0 62 0 0 0 0 0 24 0 % T
% Val: 0 8 0 70 0 0 0 24 85 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _